MAPS: Harris County ZIP codes with highest case rates for STDs, STIs

HOUSTONHarris County Public Health released its 2015–2022 report on HIV and STI cases per ZIP code across the county.

HIV, chlamydia, gonorrhea, and syphilis are all notifiable conditions in Texas.

Difference between STDs and STIs

Before we dive into the numbers, it’s important to note the difference between the two.

According to the Centers for Disease Control and Prevention (CDC), a sexually transmitted infection (STI) is a virus, bacteria, fungus, or parasite that people can get through sexual contact. An STI is curable.

A sexually transmitted disease (STD) develops as a result of an STI, and the term implies that the infection has led to symptoms or complications. An STD is generally incurable.

Harris County surpasses state averages in STIs

According to HCPH, Harris County’s rates have consistently been higher than the state averages for all STIs between 2016 and 2022. Rates increased across all conditions during this time as the population grew in Harris County and Houston.

Chlamydia has been identified as the most common STI in Harris County, with a case rate increase of 11% between 2016 and 2022. It is most prevalent in women and disproportionately affects the Black community.

Harris County Precinct 1 contains all top ZIP codes for gonorrhea and syphilis and two of the top three for chlamydia.

The ZIP codes listed likely reflect dense populations, high levels of testing, or underserved communities with barriers to prevention and care.

By the numbers

Chlamydia in Harris County – top ZIP codes

ZIP CodePrecinctNotes
77030Precinct 1Includes Texas Medical Center; may reflect high testing/reporting.
77507Precinct 2Southeast area; smaller population but high case rate.
77002Precinct 1Downtown Houston area; also high for other STIs.
Accumulated rate of chlamydia by ZIP code in Harris County, 2015–2021 (Copyright 2025 by KPRC Click2Houston - All rights reserved.)

Gonorrhea in Harris County – top ZIP codes

ZIP CodePrecinctNotes
77030Precinct 1Repeats as high for chlamydia—possible reporting density.
77002Precinct 1Central Houston, overlapping with multiple STI concerns.
77051Precinct 1South Houston area; high-risk community.
Accumulated rate of gonorrhea by ZIP code in Harris County, 2015–2021 (Harris County Public Health)

HIV in Harris County: ZIP Code Hotspots

77004Precinct 1Includes Third Ward and parts of Midtown; historically impacted Black communities
77021Precinct 1Southeast Houston; appears in syphilis list as well; underserved area
77033Precinct 1South Houston; associated with high poverty and limited access to care
77051Precinct 1Also appears under gonorrhea ZIP codes; high-risk zone
77026Precinct 1Northeast of Downtown; linked to high HIV prevalence in Black communities
Accumulated rate of new HIV diagnoses by ZIP code in Harris County, 2015–2021 (Harris County Public Health)

Syphilis in Harris County – Top ZIP Codes

ZIP CodePrecinctNotes
77002Precinct 1Consistently high across all STIs.
77006Precinct 1Montrose area; historically a hotspot for MSM cases.
77021Precinct 1Southeast Houston; affected across multiple STIs.
Accumulated rate of syphilis across ZIP codes in Harris County, 2015–2021 (Harris County Public Health)

About the Author
Brittany Taylor headshot

Award-winning journalist, mother, YouTuber, social media guru, millennial, mentor, storyteller, University of Houston alumna and Houston-native.

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