A United Nations official in Sudan says at least 100 people, including 20 children and nine aid workers, have been killed in a two-day offensive by a notorious paramilitary group.

At least two people were killed and others were injured in renewed attacks by Sudan's paramilitary Rapid Support Forces on a camp in North Darfur that is sheltering around 450,000 people displaced by the war in the country.

Around 70 people were killed in an attack on the only functional hospital in the besieged city of El Fasher in Sudan.

Officials and resistance movements in Sudan say clashes between the Rapid Support Forces and the Sudanese army in Gezira province early Wednesday morning killed at least 100 people and injured dozens.

Almost seven months of war between Sudan’s military and a powerful paramilitary group have left a wave of destruction.

An aid group says heavy artillery fire killed at least 11 people and wounded 90 in a major city in conflict-torn Sudan.